Global Lifetime Analysis
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- Written by Chavdar Slavov
Typically, in time-resolved spectroscopy the multiple kinetic traces recorded in dependence of wavelength or other experimental variable are analyzed simultaneouslyi in a procedure called global analysis. The most common global analysis procedure is global lifetime analysis (GLA), where the experimental data is approximated by a discrete sum-of-exponentials function. The global parameters spanning the dataset are the lifetimes, while the pre-exponential amplitudes are determined for each kinetic trace. GLA results in the so-called decays-associated spectra (DAS), where the pre-exponential amplitudes for each lifetime component are plotted against an experimental variable, e.g. detection wavelength. The DAS is a compact representation of the kinetic information in the data.
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Details in:
Implementation and evaluation of data analysis strategies for time-resolved optical spectroscopy
Chavdar Slavov, Helvi Hartmann, Josef Wachtveitl, Analytical Chemistry, 2015, 87, 2328
See also:
The global analysis of fluorescence intensity and anisotropy decay data: second generation thoery and programs
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